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孟鲁司特钠治疗呼吸道合胞病毒毛细支气管炎的疗效及预后观察 被引量：2

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摘要 目的探讨孟鲁司特钠对呼吸道合胞病毒(RSV)毛细支气管炎患儿临床及预后的影响。方法 73例呼吸道合胞病毒毛细支气管炎患儿(年龄3～18个月)被随机分为观察组(34例)和对照组(39例)。两组患儿均采用相同的综合治疗,观察组加用孟鲁司特钠4mg每晚1次口服,连用4周。观察各组患儿喘息持续时间及住院天数,并对所有病例随访6个月,分别统计患儿出院后3月及6月再次出现活动后及夜间咳嗽、喘息、气短及呼吸困难等情况,计算完全无症状日比例及明显症状复发率。结果观察组患儿喘息持续时间(5.82±1.50)d,住院天数(7.44±1.46)d,均明显短于对照组(8.05±1.47)d和(10.15±1.73)d(P<0.05)。在随访期间,3月后随访的明显症状复发率观察组为5.9%(2/34),对照组为17.9%(7/39),差异无统计学意义(P>0.05),但观察组患儿完全无症状日比例占(85.1±16.6)%,比对照组更高(P<0.05),6月后随访的明显症状复发率11.8%(4/34),小于对照组,完全无症状日比例(81.3±13.9)%,比对照组更高,差异均有统计学意义(P<0.05)。结论口服孟鲁司特钠治疗RSV毛细支气管炎,可缩短临床喘息症状持续时间及住院时间,减少复发,改善预后。
作者 刘颖 葛秋生 顾秋枫
机构地区 北京大学深圳医院儿科
出处 《齐齐哈尔医学院学报》 2011年第3期377-378,共2页 Journal of Qiqihar Medical University
关键词 孟鲁司特钠 白三烯受体抑制剂 呼吸道合胞病毒 毛细支气管炎 婴幼儿
分类号 R562.21 [医药卫生—呼吸系统]
  • 相关文献

参考文献12

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二级参考文献23

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共引文献1282

同被引文献26

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  • 10周晓英.孟鲁司特钠治疗婴幼儿毛细支气管炎的疗效及对反复喘息的预防效果[J].中国临床药学杂志,2011,20(3):157-159. 被引量：8

二级引证文献30

齐齐哈尔医学院学报
2011年 第3期

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