摘要
目的研究静脉点滴丙种球蛋白治疗小儿毛细支气管炎,预防喘息反复发作的发生。方法选择毛细支气管炎患58例分成对照组与观察组。随访3~5年观察患儿喘息反复发作情况。结果治疗后两组患儿的嗜酸性粒细胞数均有不同程度的降低;观察组喘息反复发作的例数比对照组少,有显著性差异（P=0.024）。两组患儿喘憋缓解时间、罗音消失时间无显著差异性,观察组患儿哮鸣音消失时间比对照组早（P=0.004）。结论静脉点滴丙种球蛋白治疗毛细支气管炎,可以有效地降低毛细支气管炎患儿喘息反复发作,不能明显缓解毛细支气管炎患儿喘憋症状,但可以缩短患儿肺部哮鸣音消失的时间。
Objective To evaluate the treatment of intravenous gamma globulins in infants with capillary bronchitis to prevent repeated wheezing attacks.Methods Fifty-eight infants with capillary bronchiolitis were randomly divided into control group and treatment group.Follow-up was conducted from three to five years to observe the repeated wheezing attacks.Results After treatment,the eosinophilic granulocytes of the two groups decreased to varying degrees.Compared with the control group,the frequency of wheezing attacks in the treatment group reduced.The difference was statistically significant（P=0.024）.Two groups showed no significant difference in terms of asthmatic alleviation and rales disappearing.The disappearing time of rales was earlier in the treatment group than the control group（P=0.004）.Conclusion Intravenous gamma globulins can reduce the frequency of repeated wheezing attacks but it does not relieve wheezing symptoms obviously.However it helps shorten the disappearing time of lung rales.
出处
《实用临床医药杂志》
CAS
2012年第3期103-105,共3页
Journal of Clinical Medicine in Practice
关键词
毛细支气管炎
丙种球蛋白
喘息反复发作
capillary bronchiolitis： gamma globulins； repeated wheezing attacks；
