摘要
目的探讨乙肝肝硬化患者血小板活化指标及抗氧化能力、红细胞免疫的变化规律。方法选取2010年7月～2012年4月于本院进行治疗的37例乙肝肝硬化患者为观察组,同期进行体检的37名健康者为对照组,将两组患者的血小板活化及抗氧化能力、红细胞免疫指标进行检测及比较。结果观察组的血小板活化指标均高于对照组,血清SOD、GSH-Px及TAC均低于对照组,MDA及MPO均高于对照组,而RBC-C3bR及RFER均低于对照组,RBC-ICR及RFIR均高于对照组,且失代偿期患者的变化幅度要大于代偿期患者,差异均有统计学意义(P均<0.05)。结论乙肝肝硬化患者血小板活化指标处于较高的状态,且抗氧化能力及红细胞免疫处于低下的状态。
Objective To study the variation of platelet activation indexes,antioxidant ability and red cell immune of patients with hepatitis B liver cirrhosis.Methods Thirty-seven patients with hepatitis B liver cirrhosis in our hospital from July 2010 to April 2012 were selected as observation group,and 37 healthy personnel at the same time were selected as control group,then the platelet activation indexes,antioxidant ability and red cell immune of two groups were detected and compared.Results The platelet activation indexes of observation group were all higher than those of control group,serum SOD,GSH-Px and TAC were all lower than those of control group,MDA and MPO were higher than those of control group,RBC-C3bR and RFER were lower than those of control group,RBC-ICR and RFIR were higher than those of control group,and the change amplitude of those at decompensation were bigger than those at compensation,there were all significant differences（all P 〈0.05）.Conclusion The platelet activation indexes is in the higher state,and the antioxidant ability and red cell immune are in the lower state.
出处
《中国当代医药》
2012年第36期31-32,共2页
China Modern Medicine
关键词
乙肝肝硬化
血小板活化
抗氧化能力
红细胞免疫
变化规律
Hepatitis B liver cirrhosis
Platelet activation
Antioxidant ability
Red cell immune
Variation
