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L-苯丙氨酸生产 被引量:3

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摘要 L-苯丙氨酸(α-氨基-β-苯基丙酸)是一种必需氨基酸,人和动物不能在体内自行合成,它必须从外界摄取。L-苯丙氨酸商品化生产随着抗癌药物的制剂和氨基酸大输液的发展,尤其是低热量的二肽甜味剂(二肽甲酯,俗称天冬甜精,它是一种甜度比蔗糖高200倍的糖精)的迅速发展而急剧增加,目前国外生产能力已超过一万吨。
出处 《氨基酸杂志》 1991年第4期32-44,24,共14页
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  • 1K. Shetty,D. L. Crawford,R. A. Korus,A. L. Pometto. Amylase activity and L-phenylalanine overproduction from starch by an analog resistant mutant ofBacillus polymyxa[J] 1988,Applied Biochemistry and Biotechnology(1-3):347~355
  • 2Martyn Robinson,Rüdiger Marquardt,Johann Then,Janet McChesney,Hugh Neatherway,Gerhard W?hner,Hans M. Deger,Paul Pràve. Cloning of the gene coding for aromatic amino acid aminotransferase from anE. Coli B strain[J] 1987,Biotechnology Letters(10):673~679
  • 3Christopher Thomas Evans,Wendy Peterson,Christin Choma,Masanaru Misawa. Biotransformation of phenylpyruvic acid to l-phenylalanine using a strain of Pseudomonas fluorescens ATCC 11250 with high transaminase activity[J] 1987,Applied Microbiology and Biotechnology(4):305~312
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  • 5Christopher T. Evans,Dayle Conrad,Kim Hanna,Wendy Peterson,Christin Choma,Masanaru Misawa. Novel stabilization of phenylalanine ammonia-lyase catalyst during bioconversion of trans-cinnamic acid to l-phenylalanine[J] 1987,Applied Microbiology and Biotechnology(5):399~405
  • 6Christopher T. Evans,Kim Hanna,Dayle Conrad,Wendy Peterson,Masanaru Misawa. Production of phenylalanine ammonia-lyase (PAL): isolation and evaluation of yeast strains suitable for commercial production of l-phenylalanine[J] 1987,Applied Microbiology and Biotechnology(5):406~414
  • 7Katsühiko Nakamichi,Yutaka Mishida,Koichi Nabe,Tetsuya Tosa. Production of L-phenylalanine from acetamidocinnamic acid usingBacillus sphaericus andParacoccus denitrificans[J] 1985,Applied Biochemistry and Biotechnology(5):367~376

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