摘要
从54例视网膜母细胞瘤(Rb)实体瘤体外培养研究中,在我国首先建成一个人类Rb连续细胞系:SO-Rb50,至今已连续传代32个余月,275代.形态学观察、免疫组化反应、染色体分析及裸小鼠皮下移植成瘤,均证实SO-Rb50细胞系是视网膜母细胞瘤细胞系.
A human retinoblastoma(Rb) continuous cell line,SO-Rb50,was first established in China from a series of 54 retinoblastoma tissue cultures. Up to now it has been maintaining in cotinuous culture for more than 32 months(275 passages). The morphology,immunohistochemical reactions,chromosomal analysis and tumor formation after subcutaneous transplantation to athymic nude mouse proved that the SO-Rb50 cell line is a retinoblastoma cell line.
出处
《中山医科大学学报》
CSCD
1991年第3期173-177,共5页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
细胞系
视网膜
细胞瘤生物学
特性
Retinoblastoma cell line Morphology Immunohistochemistry Chromosomal aberration Heterotum origenesis
