摘要
目的 了解在性病门诊中，以生殖器溃疡为主要表现的疾病的病因。方法 在实验室建立了同时检测梅毒、生殖器疱疹和软下疳的复合 PCR方法。同时进行暗视野显微镜检查和梅毒血清学检查。结果 复合 PCR检测梅毒与暗视野显微镜检查和梅毒血清学检查有较好的一致性。在总计 165例患者中，梅毒 51例，生殖器疱疹 52例，分别占 30.9％和 31.5％，未发现软下疳病例。 62例（ 37.6％）未检出病原体。结论 在性病门诊中，生殖器溃疡性疾病以梅毒及生殖器疱疹占优势，而软下疳尚未发现。
Objectives To investigate the etiology of genital ulcer diseases in sexually transmitted disease clinics. Methods The specimens from genital ulcers of 165 patients attending sexually transmitted disease clinics were detected for Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus by a multiplex PCR, dark field microscopy and syphilitic serology. Results There were 51 (30.9％ ) cases of syphilis and 52 (31.5％ ) cases of genital herpes among 165 patients, respectively. No chancroid case was found. No pathogen was detected in remaining 62 (37.6％ ) patients. Conclusion Syphilis and genital herpes predominate in genital ulcer diseases in our sexually transmitted disease clinic patients.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2000年第3期165-166,共2页
Chinese Journal of Dermatology
关键词
生殖器溃疡
梅毒
生殖器疱疹
软下疳
PCR
Genitalia Ulcer Syphilis Genital herpes Polymerase chain reaction
