摘要
目的分析探讨食管胃静脉曲张破裂出血患者死亡危险因素,临床防治提供参考依据。方法选取128例食管胃静脉曲张破裂出血患者,对其临床资料进行回顾性分析,研究相关的临床参数和各项实验室指标与患者死亡的关系。结果 128例患者经积极治疗后,15例(11.72%)患者死亡(死亡组)、113例好转或治愈出院(存活组)。对两组患者的临床参数及各项实验室指标进行统计分析结果显示,死亡组肝硬化并发HCC、Child-Pugh分级、腹水、PSE及初次内镜治疗后24 h内发生再出血者与存活组比较,差异具有统计学意义(P<0.05)。死亡组血钠水平明显低于存活组,血清胆红素及血清肌酐水平明显高于存活组,差异具有统计学意义(P<0.05)。结论食管胃静脉曲张破裂出血患者死亡危险因素有多种,临床上应加强相关指标的监测,同时采取必要的防治措施,以降低患者死亡率,改善预后。
Objective To analyze and discuss the risk factors for death of esophageal variceal bleeding, and to provide a reference for clinical treatment. Methods Choosed 128 patients with esophageal and gastric varices bleeding patients, to analyzed heir clinical data tretrospectively, and to study the relationship between clinical parameters and laboratory param- eters of patients died. Results A total of 128 patients after active treatment, 15 cases （11.72%） patients died （death group）, 113 patients improved or cured （survival group）. Statistical analysis showed that death group cirrhosis complicated by HCC, Child-Pugh classification, ascites, PSE and initial endoscopic treatment within 24 hours after rebleeding and survival of the two groups of patients with clinical parameters and laboratory parameters group, the difference was statistically significant （P 〈 0.05）. Sodium levels of the death group was significantly lower than the survival group, serum bilirubin and serum cre- atinine levels significantly higher than the survival group compared the difference was statistically significant （P 〈 0.05）. Conclusion The patients with esophageal variceal bleeding had a variety of risk factors for death, should be strengthened in the clinical monitoring of relevant indicators, at the same time to take the necessary preventive measures to reduce the mortality rate of patients and improve prognosis.
出处
《中国现代医生》
2012年第36期40-41,44,共3页
China Modern Doctor
