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鲍氏不动杆菌生物膜的研究进展 被引量:11

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摘要 近年来,鲍氏不动杆菌已逐渐成为医院感染的主要病原菌之一,其耐药性呈增长趋势,2009年多药耐药及泛耐药鲍氏不动杆菌总检出率分别高达44.4%和17.0%,已成为ICU、烧伤病房细菌感染的重要病原菌。其耐药机制除产β-内酰胺酶、氨基糖苷类修饰酶、外膜通透性改变和主动外排系统等外,还与生物膜的形成密切相关。绝大多数临床分离株鲍氏不动杆菌具有较强的生物膜形成能力,当其形成生物膜后对抗菌药物的抗性显著提高,给临床治疗带来了极大困难。因此,笔者对鲍氏不动杆菌生物膜的近期研究进展作一综述。
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2012年第23期5428-5430,共3页 Chinese Journal of Nosocomiology
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共引文献219

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