摘要
目的分析脾动脉血流栓塞术（FSE）治疗脾功能亢进的治疗效果和安全性。方法36例肝癌患者均为肝硬化并脾大，脾功能亢进，在肝癌栓塞同时行脾脏栓塞，术后3、7、30d和3个月检查白细胞、血小板，观察术后临床反应。结果术后3、7、30d和3个月白细胞[（9．4±2．1）×10^9/L、（9．3±2．3）×10^9／L、（8．6±2．1）×10^9／L、（6．4±1．6）×10^9／L与（2．6±1．4）×10^9／L]、血小板计数[（94±23）×10^9／L、（140±32）×10^9／L、（136±38）×10^9／L、（119±26）×10^9／L与（32±18）×10^9／L]与术前比较均明显升高，差异均有统计学意义（P均〈0．01）。所有患者术后均出现发热、食欲下降、恶心、脾区不适，均有脾区疼痛，其中6例需临床对症处理，左侧胸水3例，均无严重并发症发生。结论功能性脾动脉血流栓塞术是治疗肝硬化所致脾功能亢进的一种安全有效的方法。
Objective To retrospectively analyze the efficacy and safety of splenic embolization in the treatment of hypersplenism. Methods Thirty-six cases of hepatocellular carcinoma patients with cirrhosis, splenomegaly and hypersplenism underwent hepatocellular carcinoma embolization as well as with spleen embolization. White blood cells （WBC） and platelets were tested and postoperative clinical reactions were observed at 3,7,30 days and 3 - 6 months after the operation. Results The number of WBC and platelet were both significantly increased after the operation, the difference was significantly statistical [ WBC ： 3 d ：（9.4±2.1）×10^9/L、（9.3±2.3）×10^9/L、（8.6±2.1）×10^9/L、（6.4±1.6）×10^9/L与（2.6±1.4）×10^9/L months： （ 119±26）×10^9/L vs （32 2 18） ×10^9/L,P 〈0. 01 ]. All patients got fever,loss of appetite, nausea and pain in the spleen, of which 6 patients needed clinical treatment to control symptoms and left pleural effusion occurred in 3 patients, but without cases with serious complications. Conclusion The functional splenic artery blood flow embolization is a safe and effective treatment for liver cirrhosis caused by hypersplenism.
出处
《中国综合临床》
2012年第12期1328-1330,共3页
Clinical Medicine of China
关键词
脾栓塞
脾功能亢进
白细胞
Partial splenic embolization
Hypersplenism
Leukocyte
