摘要
目的 :评价平阳霉素碘油乳剂 (PLE)肝动脉栓塞对原发性肝癌肿瘤血管的祛血管作用及其强度和相应临床疗效。方法 :对 11例原发性肝癌肝动脉注入PLE ,同期 18例原发性肝癌以丝裂霉素碘油乳剂 (MLE)作对照 ,观察并比较两组栓塞后肿瘤血管及肿瘤体积变化。结果 :PLE组和MLE组栓塞后肿瘤血管均明显减少 (P <0 .0 1) ,而前者较后者减少更显著 (P <0 .0 1)。栓塞后 1～ 3个月复查两组肿瘤血管均明显缩小 (P <0 .0 5 ) ,但组间变化无明显差异 (P >0 .0 5 )。结论 :PLE对原发性肝癌肿瘤血管有祛血管作用 ,其强度大于MLE。
Objective:To evaluate the devascular effect (DE) of pingyangmycin-lipiodol emulsion(PLE) on tumor vessel of primary hepatocellular carcinoma (PHC), and investigate the curative effects of PLE embolization.Methods:Hepatic arterial embolization was performed with PLE (n=11) in PHC,and mytomycin-lipiodol emulsion (MLE) as a contrast group (n=18).The changes of the quantity of tumor vessel and tumor size were reviewed and compared.Results:The tumor vessels of primary hepatocellular carcinoma in PLE and MLE groups had significantly decreased ( P <0.01).This was more significant in the PLE-groups ( P <0.01). The tumor size of two groups decreased after 1～3 months of the procedure( P <0.05),but there was no significant difference between two groups( P >0.05).Conclusions:PLE has DE to tumor vessel of primary hepatocellular carcinoma,it is stronger than that of MLE,and tumor size decreases at the same period.
出处
《放射学实践》
2000年第2期96-98,共3页
Radiologic Practice
基金
国家九五攻关课题!资助 (课题号 :96 90 7 0 3 0 1 )
关键词
平阳霉素-碘油
动脉栓塞
药物疗法
原发性肝癌
Pingyangmycin-lipiodol Emulsion Arterial Embolization Primary hepatocellular carcinoma Clinical application
