摘要
目的 为了研究胃癌单克隆抗体的表达及临床意义。方法 用本室制备的对胃癌有较强特异性的McAbGMG1:1D1 2对 15 1例内窥镜活检组织压印片进行免疫组织化学检查。结果 用本法检查组织印片中的癌细胞以及具有癌细胞相关抗原的癌前病变组织 ,特异性强 ,反应灵敏 ,结果可靠。结论 如果与内窥镜和常规病理学检查联合应用 ,会提高早期癌的检出率 。
Objective In order to study the expression and cinical significance of McAb against gastric carcinoma.Methods 151 samples of print/press sections from gastric endoscope biopsy were examined by the monoclonal antibody GMG1:1D 2 which was specific to gastric carcinoma and made by authors laboratory.Results The results showed that the method had a high specificity and sensitivity for examination and recognition of the gastric carcinoma cells and cells of precancerous lesions with related antigen of carcinomatous cells in print sections and the examination results was reliable.Conclusion It is clear that the method is very useful to promote the diagnosis rate of earlier lesion,especially combining the endoscopy and routine pathological examination.The relationship of McAb and CP was also discussed in this paper.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2000年第2期119-121,共3页
Cancer Research on Prevention and Treatment
关键词
单克隆抗体
幽门弯曲菌
癌前病变
胃癌
Monoclonal antibody
Camplobacter pyloridis
Precancerous lesions
