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微小RNA在2型糖尿病相关机制中的研究进展 被引量：6

Progress of microRNAs involved in type 2 diabetes mellitus
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摘要 2型糖尿病及其慢性并发症严重威胁人类健康，但其确切发病机制并不十分清楚。微小RNA是一种非编码单链RNA，参与2型糖尿病等多种疾病的发生。微小RNA在胰岛素抵抗、胰岛功能缺陷这两个2型糖尿病主要病理生理过程及其并发症发生中的重要作用引发越来越多的关注。 Type 2 diabetes mellitus （T2DM） is one of the most serious public health problems, while the detailed mechanisms underlying its pathology remain obscure. MicroRNAs （miRNAs） , which are single-stranded noncoding RNAs, are considered to be involved in various pathological processes, especially in T2DM. MiRNA has become a noval player in insulin resistance, islet dysfunction, and even in the diabetes related complications.
作者 张冬雪 陈璐璐 廖云飞
机构地区 华中科技大学同济医学院附属协和医院内分泌科
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2012年第11期944-947,共4页 Chinese Journal of Endocrinology and Metabolism
基金 国家自然科学基金资助项目（81070648,81100580）
关键词 微小RNA 糖尿病 2型 胰岛素抵抗 胰岛功能缺陷 糖尿病并发症 microRNA Diabetes mellitus, type 2 Insulin resistance Islet dysfunction Diabetes relatedcomplications
分类号 R587.1 [医药卫生—内分泌]
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共引文献16

同被引文献84

  • 1杨慧霞.妊娠合并糖尿病临床诊断与治疗推荐指南(草案)[J].中国实用妇科与产科杂志,2007,23(6):475-477. 被引量：374
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引证文献6

二级引证文献42

中华内分泌代谢杂志
2012年 第11期

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