摘要
阻塞性睡眠呼吸暂停综合征(OSAS)是一种以睡眠状态下反复发生呼吸暂停和(或)低通气为主要表现的并发多器官损害的临床综合征。近年研究表明,OSAS与高血压、冠心病、心律失常、心力衰竭、猝死等心血管疾病的发生联系密切,其机制可能与OSAS导致的低氧血症、高碳酸血症、炎症、氧化应激、自主神经功能紊乱、血管内皮功能紊乱等有关,但其具体病理生理机制尚不明确。
Obstructive sleep apnea syndrome（OSAS）is characterized by repetitive apnea and/or hypopnea during sleep,and it can cause multiorgan dysfunction.Recent researches have shown OSAS is closely correlated with hypertension,coronary heart disease,arrhythmia,heart failure,and sudden death.Its definite mechanism is undefined,which may be related to hypoxemia,hypercapnia,inflammation,oxidative stress,and dysfunction of autonomic nerve and endothelium.
出处
《医学综述》
2012年第21期3658-3660,共3页
Medical Recapitulate
