摘要
目的 :应用二维斑点追踪成像(Two-dimensional speckle tracking imaging,2DSTI)技术测量2型糖尿病(Type 2diabetes mellitus,T2DM)患者左室心肌旋转指标,探讨2DSTI技术评价T2DM患者左室心肌旋转运动的临床价值。方法 :采集43例T2DM患者(无微血管病变组20例,合并微血管病变组23例)和30例正常人的左室短轴二尖瓣水平、心尖水平切面二维高帧频声像图,测量内膜下(Prot-endo)、外膜下(Prot-epi)、切面整体(Prot)及跨壁角度梯度峰值(Prot-mur)。结果:①从正常对照组到糖尿病合并微血管病变组心尖水平Prot-endo、Prot-epi、Prot、二尖瓣水平Prot-epi递增(P<0.05),而心尖水平Prot-mur递减(P<0.05);②糖尿病合并微血管病变组的二尖瓣水平Prot-endo较正常对照组增高(P<0.05);③与正常对照组比较,糖尿病患者的二尖瓣水平Prot-mur减低、二尖瓣水平Prot增高(P<0.05)。结论:2DSTI技术能够准确测量T2DM患者左室短轴二尖瓣水平、心尖水平切面Prot-endo、Prot-epi、Prot及Prot-mur的变化,敏感评价T2DM患者心功能状态。
Objective： To observe the rotation parameter of left ventricular short-axis views in the subendocardial and subepicardial myocardium layers by two-dimensional speckle tracking imaging （2DST1）, and to evaluate its performance in patients with type 2 diabetes mellitus（T2DM）. Methods： Fourty-three patients with T2DM（20 patients without microangiopathy, 23 patients with microangiopathy）, and 30 cases of healthy volunteers as control were included in the study. High frame rate dynamic two-dimensional images were recorded at the left ventricular short-axis view, including basal and apical planes. The peak subendoeardial rotation（Prot-endo）, peak subepicardial rotation（Prot-epi）, peak bulk rotation（Prot）, and peak mural rotation （Prot-mur） were measured. Results： ①The apical Prot-endo, Prot-epi, Prot and the basal Prot-epi were higher and the apical Prot-mur was lower in control group than the T2DM group with microangiopathy （P〈0.05）. ②The basal Prot-endo of T2DM patients with mieroangiopathy was significantly lower than that in control group. ③When compared to the control group, the basal Prot-mur decreased while the basal Prot increased in the T2DM group（P〈0.05）. Conclusions： The 2DSTI can accurately evaluate the characteristics of left ventricular rotation parameter and sensitively evaluate the cardiac function in patients with T2DM.
出处
《中国临床医学影像杂志》
CAS
2012年第10期703-706,共4页
Journal of China Clinic Medical Imaging
关键词
糖尿病
2型
心室功能
左
心肌
超声心动描记术
多普勒
彩色
Diabetes mellitus, type 2
Ventricular function, left
Myocardium
Echocardiography, Doppler, color
