摘要
目的探讨瞬时波强（wI）技术评价糖调节受损者左室收缩功能的临床价值。方法72例研究对象按照血糖水平分为三组：A组，血糖正常组；B组，新增空腹血糖受损组；C组，糖尿病前期组。应用wI技术测量两个正向波（W1、W2）、僵硬度（B）、压力应变弹性系数（Ep）、顺应性（AC）等指标，同时应用常规超声心动图测量左室射血分数（LVEF）、左室缩短分数（LVFS）及二尖瓣环收缩期最大运动速度（Sin），比较各组间左心室收缩功能指标的差异。结果与A组比较，C组的W1、W2、B、Ep均明显增高，AC减低，差异有统计学意义（P〈0．05）；R—w1、W1—W2差异无统计学意义（P〉0．05）。常规超声心动图指标中，C组Sm明显减低（P〈0．05），而各组间LVEF、LVFS差异无统计学意义（P〉0．05）。B组与A组各指标比较差异无统计学意义（P〉O．05）。结论wI对评价糖调节受损者左室收缩功能较常规超声心动图指标更敏感、更客观，具有一定的临床应用价值。
Objective To explore the clinical value of wave intensity（WI） in assessing left ventricular systolic function of patients with impaired glucose regulation. Methods 72 people were involved in this study, according to their plasma glucose levels, subjects were categorized as normal plasma glucose group （group A）,newly categorized impaired fasting glucose group （group B） and pre-diabetes group （group C）. Carotid WI examination was performed and analyzed. The parameters included magnitude of the peak during early systole （W1）, amplitude of the peak during late systole （W2）, interval between R wave of electrocardiogram and W1 （R-W1）, interval between W1 and W2 （W1-W2）, stiffness parameter （13）, pressure strain elasticity modulus（Ep） and arterial compliance（AC）. Echocardiographic indices including left ventricular ejection fraction （LVEF）,left ventricular fraction shortening （LVFS） and the peak velocity of mitral annulus at systolic phase（Sm） were determined in each subject. Results Compared to group A,W1, W2,I3,Ep increased significantly while AC decreased in group C（ P 〈0.05）. However, this difference did not persist in group B. Compared to group A,LVEF and LVFS were not observed significantly different in group B and group C. Conclusions WI is a hemodynamic method which not only can evaluate left ventricular systolic function of impaired glucose regulation subjects but also be more sensitive than routine echocardiography.
出处
《中华超声影像学杂志》
CSCD
北大核心
2014年第2期113-116,共4页
Chinese Journal of Ultrasonography
基金
郑州市2010年度科技攻关项目（2010SFXM175）
关键词
超声心动描记术
心室功能
左
糖尿病前期
瞬时波强
Echocardiography
Ventricular function,left
Prediabetic state
Wave intensity
