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右美托咪定在腹腔镜手术中的应用

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摘要 探讨右美托咪定(α2肾上腺素受体激动剂)在腹腔镜手术中的有效性和安全性。将40例进行腹腔镜手术的患者(ASAⅠ~Ⅱ级)随机分为实验组和对照组,每组各20例。实验组在气管插管术开始前10min静脉泵注右美托咪定(0.6μg/kg),对照组在气管插管术开始前10min静脉泵注同剂量的生理盐水,泵注时间均为10min。观察记录两组患者术前、切皮、拔管时及术后1h的心率、血压、脑电双频指数(BIS)和拔管时间。和麻醉前比较切皮时及拔管时,实验组血压、心率无明显变化;对照组心率明显增快和血压明显升高(P〈0.05)。切皮时实验组BIS明显低于对照组(P〈0.05)。
作者 吴秀莲
出处 《中国医药指南》 2012年第29期503-504,共2页 Guide of China Medicine
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