盐酸右美托咪啶用于围术期镇静及预防气管插管反应的临床研究被引量：28

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摘要盐酸右美托咪啶（dexmedetomidine,DEX）是一新型的α2肾上腺素能受体（α2 AR）激动剂,与可乐定相比,具有高选择性、高特异性等优点,受体选择性（α2∶α1）为1 620∶1,可乐定为220∶1,DEX的活性强于可乐定,其分布半衰期约5 min,清除半衰期约2 h。DEX具有剂量依赖性镇静、

作者张海山

机构地区胜利油田中心医院麻醉科

出处《第三军医大学学报》 CAS CSCD 北大核心 2011年第21期2319-2320,共2页 Journal of Third Military Medical University

关键词盐酸右美托咪定 Α2肾上腺素能受体激动剂全身麻醉镇静应激反应

分类号 R971 [医药卫生—药品]

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