摘要
难治性癫痫是最棘手的临床问题之一,其病因至今未明。由于人体脑组织难以获取等限制,难治性癫痫发生机制的研究需依赖动物模型。本文对不同难治性癫痫动物模型的制作方法、表现和机制等方面作综述。
Refractory epilepsy is one of the most thorny subject and its etiology is unkown. Attempts to study in vivo are harmpered by the lack of suitable brain tissue from patients with refractory epilepsy or controls. Nevertheless, an animal model would be a valuble tool to study mechanisms of refractory epilepsy and to develop more effective treatment approach. This paper reviews establishment, features and mechanism of animal model of refractory epilepsy.
出处
《中国现代医生》
2012年第30期11-12,15,共3页
China Modern Doctor
基金
国家自然科学基金(20100471542)
山东省山东大学科技发展计划项目(201003120)
关键词
难治性癫痫
动物模型
进展
Refractory epilepsy
Animal model
Progress
