摘要
目的:为促进临床合理用药和进一步评价药品安全风险提供参考。方法:收集我院2008年1月1日-2011年12月31日的ADR报告142份,分别从ADR报告来源、患者性别及年龄分布、ADR的关联性评价、ADR涉及药品种类、给药途径、ADR累及器官或系统及主要临床表现、ADR分级及转归等方面进行统计、分析。结果:142份ADR报告中,涉及药品以抗感染药居多(占30.99%);静脉给药方式是导致ADR的主要给药途径(占71.83%);ADR最常见的临床表现为皮肤及其附件损害(占42.25%)。结论:临床应充分评估用药安全风险,提高合理用药水平,减少或避免ADR的重复发生。
OBJECTIVE： To provide reference for the improvement of rational drug use and further evaluation of drug safety risk. METHDOS： 142 ADR cases collected from our hospital during Jan.lst, 2008 to Dec.31st, 2011, were analyzed statistically in respect of ADR source, patient＇s gender, age distribution, ADR correlation evaluation, drug category, routes of administration, organs and systems involved and clinical manifestations, classification and outcome of ADR. RESULTS： Of 142 ADR cases, 30.98% were induced by anti-infective drugs, 71.82% were induced by intravenous administration, and lesion of skin and its ap- pendants were the most common manifestations （42.25%）. CONCLUSION： Medication risk should be evaluated and rational drug use should be improved to avoid or reduce the reoccurrence of ADR.
出处
《中国药房》
CAS
CSCD
2012年第42期4002-4004,共3页
China Pharmacy
