摘要
目的:分析我院儿童药品不良反应发生的特点及规律,为儿童临床安全用药提供参考。方法:采用回顾性研究的方法,对我院2012年3月-2016年6月收集上报的176份ADR报告进行统计分析。结果:176例儿童ADR中,男性102例(57.95%),女性74例(42.05%);年龄在6岁以下的患儿ADR发生率最高(81.26%);静脉给药引发ADR居多,有153例(86.93%);抗菌药物引发的ADR居首位,涉及20个药品品种,共有106例(60.23%);皮肤及其附件损害是ADR最主要的表现,共127例(50.60%)。结论:应加强对儿童ADR监测,多方配合,促进临床合理用药,以减少和预防ADR发生。
OBJECTIVE：To analyze the characteristics and rules of pediatric adverse drug reaction（ADR） in our hospital,and provide reference for clinical safe drug use. METHODS：Retrospective study was adopted to statistically analyze the ADR reports in our hospital from Mar. 2012 to Jun. 2016. RESULTS：In the 176 ADR reports,102 were male（57.95%）and 74 were female（42.05%）;children younger than 6 years old had the highest incidence of ADR（81.26%）;intravenous administration induced 153 cases（86.93%）,the top one was antibiotics,which involving 20 antibiotics,totally 106 cases（60.23%）;skin and its appendages damage were the main manifestations,totally 127 cases（50.60%）. CONCLUSIONS：Pediatric ADR monitoring should be strengthened,dinical rational drug use should be promoted by cooperation in many ways to reduce and prevent the inciderle of pediatric ADR.
出处
《中国药房》
CAS
北大核心
2016年第26期3649-3651,共3页
China Pharmacy
关键词
儿童
药品不良反应
合理用药
Children
Adverse drug reaction
Rational drug use
