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微小RNA在结直肠癌临床诊断中的作用及其研究进展 被引量:2

MicroRNAs in clinical diagnosis of colorectal cancer and recent advances
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摘要 随着研究的深入,发现微小RNA(miRNAs)在结直肠癌发生发展过程中扮演着重要角色,笔者就miRNAs上调和下调与结直肠癌(CRC)的关系,miRNAs表达的改变对CRC诊断、分期的影响及其应用前景等方面的研究进展进行综述。 With the deepening of the investigations, the critical role of microRNA (miRNAs) in the occurrence and development of colorectal cancer has been established. This paper overviews the relations of up- and down- regulation ofmiRNAs with colorectal cancer, the influences of the alterations of miRNAs on the diagnosis and staging of colorectal cancer, and the prospects of their possible application in the future.
出处 《中国普通外科杂志》 CAS CSCD 北大核心 2012年第10期1275-1278,共4页 China Journal of General Surgery
关键词 结直肠肿瘤/诊断 微RNAS 临床应用 综述文献 Colorectal Neoplasms/diag MicroRNAs Clinical Application Review
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