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MicroRNA在结直肠癌中的研究进展 被引量:3

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摘要 MicroRNA又称miRNA,是一类长约22个核苷酸、单链、内源性、高度保守的非编码小分子RNA,参与增殖、分化、凋亡等多种重要细胞活动的调控,并与肿瘤的关系密切:研究发现mIRNA具有癌基因和抑癌基因样的作用,在多种肿瘤(包括结直肠癌)的发生、发展、侵袭、转移中发挥重要作用、这些发现极大的扩展了结直肠癌的发病机制,
出处 《中华外科杂志》 CAS CSCD 北大核心 2010年第17期1345-1347,共3页 Chinese Journal of Surgery
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