摘要
目的观察舒肝解郁胶囊治疗肠易激综合征(IBS)的效果。方法 60例IBS患者随机分为舒肝解郁组、黛力新(氟哌噻吨美利曲辛片)组和对照组。对照组给予马来酸曲美布汀和双歧杆菌活菌制剂口服;舒肝解郁组口服舒肝解郁胶囊0.72mg,2次/d;黛力新组口服氟哌噻吨美利曲辛片10.5mg,2次/d。疗程均为4周,观察3组患者的治疗总有效率,并比较焦虑自评量表(SAS)、抑郁自评量表(SDS)得分。结果治疗后舒肝解郁组和黛力新组患者SAS、SDS评分均较治疗前明显降低(P<0.05);总有效率、SAS、SDS二者差异无统计学意义(P>0.05),与对照组比较差异有统计学意义(P<0.05)。3组均无明显不良反应。结论舒肝解郁胶囊治疗IBS在改善临床症状、降低不良情绪等方面与氟哌噻吨美利曲辛疗效相当,副作用少,值得临床推广。
Objective To observe the effect of shuganjieyu capsules for irritable bowel syndrome （IBS）. Methods Sixty pa- tients with IBS were randomly divided into three groups, shuganjieyue group, deanxit group and control group. Control group was treated with oral trimebutine maleate casules and bifidobiogen-livzon capsules. Shuganjieyu group was received 0.72 mg oral sbuganjieyu capsules twice daily for 4 weeks. Deanxit group was received 10.5 mg oral Deanxit capsules twice daily for 4 weeks. Total effective rate of three groups were observed. Meanwhile, self-rating depression scale （SDS） and self-rating anxiety scale （SAS） were compared. Results In shuganjieyu group and deanxit group, SDS and SAS were signif- icantly decreased （P 〈 0.05）; the difference of total effective rates, SDS and SAS had no significant difference （P 〉 0.05）. But the difference was obvious compared with control group （P 〈 0.05）. All patients had no signifieant adverse effects. Conclusion Shuganjieyu capsule has exact curative effect for IBS.
出处
《中国当代医药》
2012年第27期119-120,共2页
China Modern Medicine
关键词
肠易激综合征
舒肝解郁胶囊
氟哌噻吨美利曲辛片
疗效
Irritable bowel syndrome
Shuganjieyu capsules
Flupentixol and melitracen tablets
Effect
