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曲美他嗪对缺血性心力衰竭患者心率变异性的影响 被引量：10

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摘要 目的评价曲美他嗪对缺血性心力衰竭患者心率变异性的影响。方法选择缺血性心肌病心衰患者30例,在常规抗心衰治疗(利尿剂、血管紧张素转换酶抑制剂/血管紧张素受体抑制剂、β受体组滞剂、醛固酮拮抗剂及洋地黄制剂)基础上加服曲美他嗪20mg,每日3次,连用3个月。以超声心动图和24h动态心电图分别观察治疗前、治疗后3月心脏功能和心率变异性的改变情况。结果曲美他嗪使用后左室射血分数由(33.5±5.1)%增加到(42.5±5.8)%(P<0.001)。心率变异性分析表明,使用曲美他嗪后,正常R-R间期标准差(SDNN,97.3ms±40.1ms vs 110.5ms±29.2ms,P=0.049)和连续5min正常R-R间期均值标准差(SDANN,80.5ms±29.0ms vs 98.3ms±30.5ms)均较使用前显著增加。结论曲美他嗪能够在一定程度上改善缺血性心肌病心衰患者心率变异性,改善心脏功能。
作者 黄小春
机构地区 江苏省盐城市东台市中医院
出处 《中西医结合心脑血管病杂志》 2012年第9期1033-1034,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词 曲美他嗪 心率变异性 心力衰竭
分类号 R541.6 [医药卫生—心血管疾病] R256.2 [医药卫生—中医内科学]
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参考文献16

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同被引文献70

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中西医结合心脑血管病杂志
2012年 第9期

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