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白细胞介素-6与低氧性肺动脉高压关系的探究 被引量:1

Relationship between interleukin-6 and hypoxic pulmonary hypertension
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摘要 肺动脉高压(PAH)是一种常见的临床症状,凡是能引起血管阻力增大、血流量增多的因素都可成为其诱因。低氧性肺动脉高压(HPH)则是以低氧性肺动脉收缩和低氧性肺血管重构引起的肺动脉压持续升高为特征的病症。急、慢性低氧均可引起白细胞介素-6(IL-6)的分泌,导致炎症细胞浸润,继而通过对动脉内膜的改建引起PAH。 Pulmonary artery hypertension (PAH) is a common syndrome that can be induced by stronger vascular resistance and increased blood flow. Hypoxic pulmonary hypertension (HPH) is a syndrome characterized by hypoxia-induced pulmonary artery resistance and hypoxia-induced pulmonary vascular remodeling. Both acute and chronic hypoxia can cause interleukin-6 secretion, which induces PAH through endarterial remodeling.
出处 《心脏杂志》 CAS 2012年第5期663-666,共4页 Chinese Heart Journal
关键词 白细胞介素-6 低氧 肺动脉高压 interleukin-6 hypoxia hypertension, pulmonary
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