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CD14^+CD16^+亚型单核细胞的研究进展 被引量：9

Research progress of CD14^+CD16^+ subtypes monocytes
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摘要 目前已经确定的外周血单核细胞有4种亚型,最主要的有2种,分别是CD14++CD16-和CD14+CD16+单核细胞。两种主要亚型的单核细胞在趋化因子受体、黏附分子的表达以及在迁移和分化特性上都是不同的。近年来发现CD14+CD16+细胞的促炎症细胞因子是高表达的,也是具有较高抗原提呈能力的细胞。本文对单核细胞的亚型,CD14+CD16+细胞的主要特性,以及这一群CD14+CD16+单核细胞对于人类相关的一些疾病的影响进行简要综述。 Peripheral blood mononuclear cells（PBMCs） have 4 different kinds of subtypes,and the two main subtypes are CD14＋＋ CD16-and the CD14＋CD16＋.There are significant differences on expression level,migration and differentiation function of chemokine receptor,and adhesion molecule between the two subtypes.As a main signal molecule of higher expression inflammatory factor and antigen,CD14＋CD16＋ cells are elucidated recently.the main characters on CD14＋CD16＋ cells and their function on diseases of human will be summarized in the following review articles.
作者 王鑫 康富标 王桂平 张国民
机构地区 承德医学院附属医院消化内科 白求恩国际和平医院感染肝病科 承德医学院附属医院医务处 承德医学院附属医院感染病科
出处 《免疫学杂志》 CAS CSCD 北大核心 2012年第10期910-913,共4页 Immunological Journal
关键词 单核细胞 亚型 炎症 抗原提呈 Monocytes Subtype Inflammation Antigen presentation
分类号 R392.12 [医药卫生—免疫学]
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参考文献19

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二级参考文献42

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共引文献22

同被引文献105

引证文献9

二级引证文献35

免疫学杂志
2012年 第10期

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