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局部晚期非小细胞肺癌三维适形放疗致放射性肺炎危险因素分析 被引量:7

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摘要 目的:研究三维适形放疗(3D-CRT)治疗局部晚期非小细胞肺癌(NSCLC)后放射性肺炎(RP)的危险因素。方法:选择本科诊治的187例局部晚期NSCLC患者为研究对象,采用单因素和多因素分析3D-CRT治疗NSCLC后RP的危险因素。结果:NSCLC患者治疗后≥2级RP发生率为37.9%。单因素分析显示DVH中双肺MLD、V5、V10、V20、V30、V40、V50和V60中的差异具有统计学意义(均P<0.05),多因素分析表明双肺MLD和V5为3D-CRT治疗NSCLC后RP独立危险因素(均P<0.05)。结论:局部晚期NSCLC患者3D-CRT治疗后RP的发生与剂量体积直方图有关,双肺MLD和V5为独立危险因素。
出处 《实用医学杂志》 CAS 北大核心 2012年第19期3261-3263,共3页 The Journal of Practical Medicine
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