摘要
目的观察Menicon—Z硬性透气性角膜接触镜（RGPCL）控制青少年进展性近视的临床效果。方法前瞻性自身对照研究。选取18岁以下近视患者76例（148眼），按近视度分为4组（-0．50～-3．00D。-3．25～-6．00D．-6．25～-9．00D，9．25～-20．00D），分析酉B戴RGPCL（15．2±5．2）个月后的矫正视力、屈光状态、角膜地形图参数、年近视增长幅度及眼轴长度等项目的变化。采用配对样本t检验、单因素方差分析评价RGPCL控制青少年进展性近视的效果。结果配戴RGPCL后平曲率（FK）、陡曲率（SK）值均降低，差异均有统计学意义（t=4．80，P〈0．01；t=7．76，P〈0．01）；而球镜度、散光、眼轴长度变化不明显；同原近视增长幅度[（-1．10±0．53）D／年]比较，配戴RGPCL后近视增幅[（-0．00±0．47）D]年]显著降低（t=-13．95，P〈0．01）。不同近视程度组间比较，配戴RGPCL前后近视增长幅度差异有统计学意义（F=4．84．P〈0．01），较高近视度患者配戴RGPCL近视增K幅度最小。结论长期配戴Menicon—ZRGPCL安全性高．并能有效地延缓青少年不断增长的近视度、角膜曲率及眼轴长度，尤其是对较高近视度者控制的效果更为显著．
Objective To evaluate the effect of Menicon-Z gas permeable contact lenses （RGPCLs） in controlling the progression of myopia in adolescents. Methods It was a prospective self-control study. Seventy-six myopia patients under the age of 18 （148 eyes） were recruited for this study. Divided into 4 groups according to the degree of refractive error （-0.50- -3.00 D,-3.25- -6.00 D, -6.25- -9.00 D,-9.25- -20.00 D）. Clinical data included corrected visual acuity, refractive power, corneal curvature, axial length, annual progression rate of myopia and follow-up records for （15.2±5.2）months were analyzed. Data analysis included a paired samples t test and ANOVA on the effect of clinical RGPCLs to control juvenile myopia progression. Results There were significant differences in corneal curvature after wearing RGPCLs （FK t=4.80, P〈0.01 ;SK t=7.76, P〈0.01）. There were no obvious differences in refractive power, astigmatism or axial length. However, there was a significant difference in the range of myopia progression （from -1.10±0.53 D to -0.00±0.47 D） that showed a decrease after wearing RGPCLs for about 1 year （t=-13.95, P〈0.01）. There were statistically significant differences between different refractive power groups （F=4.84, P=0.004）： for higher refractive powers, myopia progression was least. Conclusion Long-term wear of Menicon-Z RGPCLs is safe for adolescents. And it effectively decreases the progression of myopia, corneal curvature and axial length, especially in more severe myopia cases.
出处
《中华眼视光学与视觉科学杂志》
CAS
2012年第9期566-568,共3页
Chinese Journal Of Optometry Ophthalmology And Visual Science
