摘要
血根碱(sanguinarine)作为一种苯菲啶异喹啉类生物碱,具有抗菌、抗炎、抗氧化、抗肿瘤、改善肝功能及诱导细胞凋亡等作用,同时对肝脏、心脏等具有一定的毒性。作者就血根碱对细菌、真菌和癌细胞的药理作用及毒性作一综述,为该药在临床中的有效合理应用奠定基础。
Sanguinarine as a benzene phenanthridine isoquinoline alkaloids with anti-bacterial, anti-inflammatory, antioxi- dant, antitumor,can improve liver function and induction of apoptosis and so on, while on the liver and heart has a certain tox- icity. In this paper, it reviewed for the drug on bacteria, fungi and cancer cells pharmacological effects and toxicity, in order to lay the foundation for effective and rational application in clinic.
出处
《中国畜牧兽医》
CAS
北大核心
2012年第7期214-217,共4页
China Animal Husbandry & Veterinary Medicine
关键词
血根碱
药理作用
毒理作用
sanguinarine
pharmacological effects
toxicological effects
