摘要
目的:探讨喹硫平治疗精神分裂症的疗效及不良反应。方法:以喹硫平与氯氮平治疗精神分裂症各40例作对照研究,采用阳性症状与阴性症状量表(PAN-SS)、不良反应症状量表(TESS)评定疗效及不良反应。结果:氯氟平组有效率90%,显效率50%;启维组有效率92%,显效率80%。喹硫平组无明显锥外系反应。结论:两组药物对精神分裂症的疗效相当,喹硫平治疗精神分裂症疗效肯定,不良反应小,安全性强。
Objective：To research the therapeutic and side effects of quetiapine in the treatment of schizophrenia patients. Methods：Eighty schizophrenia patients were treated with clozapine as the controlled group. The etticaey was measured with the positive and negative symptoms scale （PANSS）, while the adverse events were determined by the treatment emergent symploms scale （TESS）. Results：The efficacy rate of elozapine was 90%, in which 50% were improved markedly. The efficacy rate of quetiapine was 92%, in which 80% were improved markedly. Conclusion： Both groups had a smaller effect in the trentment of schizophrenia. QutiaPine had a ehara - eteristic which definite effects and side effects in the treatment of sehizophenia and had rather safety.
