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CRP、免疫球蛋白联合检测在强直性脊柱炎诊断中的应用 被引量:7

Detection of serum c-reaction protein and immunoglobulin in patients with ankylosing spondylitis
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摘要 目的探讨C-反应蛋白(CRP)、免疫球蛋白在强直性脊柱炎(AS)患者中的水平变化及其对AS的影响。方法采用免疫散射比浊法检测31例强直性脊柱炎患者与40例正常健康人血清中CRP、免疫球蛋白的水平进行比较。结果 CRP、IgA、IgG水平显著高于正常对照组(P<0.01),IgM水平与健康对照组无显著性差异(P>0.01)。结论 CRP、IgAIgG参与强直性脊柱炎的发病、发展过程,通过观察CRP、IgA、IgG的变化对强直性脊柱炎的病情活动性判断和疗效估计有重要意义。 Objective To detect the levels of serum c-reaction protein and immunoglobulin in patients with ankylosing spondylitis.Methods The levels of CRP,IgG,IgA,IgM were detected with rale-nephelometry in patients.The result of 31 patients were compared with that of 40 healthy control.Results The levels of serum CRP,IgG and IgA in AS pations were higher than in healthy control,(P0.01).There was no significant difference in levels of IgM.Conclusion The combined detection of complements,CRP and immunoglobulin in patients with ankylosing spondylitis is helpful for guidance of diagnosis and treatment of ankylosing spondylitis.
出处 《中国实用医药》 2012年第15期51-52,共2页 China Practical Medicine
关键词 强直性脊柱炎 C-反应蛋白 免疫球蛋白 Ankylosing spondylitis C-reaction protein Immunoglobulin
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