摘要
本实验采用乳酸脱氢酶释放法研究甘草甜素和甘草酸单铵对人外周血NK细胞活性的影响。结果表明,甘草甜素和甘草酸单铵本身无增强NK细胞活性的作用,但可明显促进IL-2增强NK活性,这种增强作用与甘草甜素和甘草酸单铵的浓度有关。
The effect of Glycyrrhizin(GL)and Moncammonium Glycyrrhizanate(MAG)on NK cytotoxicity from normal human peripheral blood mononuclear cells(PBMC) was studied by LDH enzyme release assay. The results showed thatthe NK cytotoxicity could be markedly augmented by GL+IL-2, or MAG+IL-2,but no such augmentation by GL or MAG itself alone. The enhancing effectrelates with the concentration of GL or MAG.
出处
《中国医科大学学报》
CAS
CSCD
1990年第6期430-432,共3页
Journal of China Medical University
关键词
甘草甜素
甘草酸单铵
NK活性
glycyrrhizin
monoammonium glycyrrhizanate
NK cytotoxicity
LDH enzyme release assay
