摘要
目的 观察多囊卵巢综合征（PCOS）患者经阴道卵巢内激光治疗和腹腔镜下打孔两种术式对妊娠和卵巢功能的影响.方法 根据知情同意原则将在本院因多囊卵巢综合征初次手术的患者分为经阴道卵巢内激光治疗组（经阴道组）和腹腔镜下卵巢打孔术组（腹腔镜组）各15例,比较治疗后6个月两组情况.结果 经阴道组和腹腔镜组治疗后自发排卵率分别为73.3 %和80.0 %;治疗后6个月累积临床妊娠率分别为46.7 %和53.3 %;治疗后第2次月经及6个月后第1次月经的第2～3天两组患者的黄体生成素（LH）、睾酮（T）、黄体生成素（LH）/卵泡刺激素（FSH）比值,经阴道组分别为（6.0±2.8）IU/L、（2.3±0.7）nmol/L、（1.2±0.3）和（6.3±2.9）IU/L、（2.2±0.7）nmol/L、（1.1±0.3）,腹腔镜组分别为（5.8±2.6）IU/L、（2.1±0.6）nmol/L、（1.1±0.4）和（5.9±2.7）IU/L、（2.2±0.6）nmol/L、（1.2±0.3）,差异均无统计学意义.结论 多囊卵巢综合征患者经阴道卵巢内激光治疗和腹腔镜下卵巢打孔能得到同样的治疗效果.
Objective To examine the effect of ultrasound - guided transvaginal ovarian interstitial laser compared with laparoscopic ovarian drilling in the treatment of patients with polycystic ovary syndrome. Methods During June 2008 and June 2010, 30 patients with polycystic ovary syndrome were treated. Patients were divided into two groups, with 15 patients treated with ultrasound - guided transvaginal ovarian interstitial laser and 15 patients with laparoscopic ovarian drilling. Serum sexual hormone level, ovulation rate, and pregnancy rate within six postoperative months were compared between the two groups. Results After treatment, spontaneous ovulation rate was 73.3 % in the transvaginal group and 80.0 % in the laparoscopic group. Six months after treatment, the cumulative clinical pregnancy rate was 46.7 % in the transvaginal group and 53.3 % in the laparoscope group. In the transvaginal group, corpus luteum （LH）, testosterone （T）, corpus luteum （LH）/follicle - stimulating hormone （FSH） ratio was （6.0±2.8 ） IU/L, （ 2.3 ± 0.7 ） nmol/L, and （ 1. 2 ±0.3 ）, respectively, on the second or third day of the second menstrual period after treatment, and （6.3±2.9） IU/L, （2.2 ± 0.7） nmol/ L, and （ 1.1±0.3）, respectively, on second or third day of the first menstrual period 6 months after treatment. These figures had no statistical differences compared with the corresponding figures of the laparoscopic group. Conclusion Polycystie ovarian syndrome patients treated with ultrasound -guided transvaginal ovarian interstitial laser is as effective as with laparoscopic ovarian.
出处
《中国生育健康杂志》
2012年第3期179-181,190,共4页
Chinese Journal of Reproductive Health
关键词
多囊卵巢综合征
激光凝固术
腹腔镜手术
不育
Polycystic ovary syndrome
Laser coagulation
Laparoscopic surgery
Infertility
