摘要
目的:探讨不同术前个体条件对B超引导下卵巢间质激光治疗PCOS的疗效有无影响。方法:选择2006年8月～2008年8月间就诊的、对克罗米芬促排卵无反应的PCOS患者60例进行B超引导下经阴道卵巢内激光治疗,根据不孕类型、不孕年限、体重指数、有无闭经、LH水平、LH/FSH比值、T水平、平均卵巢径线及平均小卵泡数等因素分别进行分组,比较上述自身因素对术后6个月内自发排卵率和累积妊娠率的影响。结果:60例患者中,术后6个月内自发排卵率为61.7%(37/60),累积临床妊娠率为53.3%(32/60)。原发不孕和有闭经病史的患者术后自发排卵率较低,但是一旦有排卵,则对妊娠率无影响;BMI和术前LH水平虽然对自发排卵率无影响,但是BMI>25kg/m2和LH≤10U/L的患者妊娠率较低。结论:继发不孕和无闭经病史的患者对B超引导下经阴道卵巢内激光治疗的反应较好,体重指数正常及LH>10U/L的患者则在术后获得较高的妊娠率。
Objective： To explore the effect factors of B ultrasound - guided ovarian interstitial laser in the treatment of polyeystic ovarian syndrome （PCOS） . Methods： From August 2006 to August 2008, 60 cases with elomifene citrate - resistant PCOS underwent B ultrasound - guided transvaginal ovarian interstitial laser treatment, then the cases were divided into two groups according to infertility types, duration of infertility, body mass index, amenorrhea or not, the levels of luteinizing hormone （LH） and testosterone （T） , the ratio of LH/ follicle -stimulating hormone （FSH）, the mean ovarian diameter and mean amount of small follicles, the ovulation rate and pregnancy rate were compared between the groups. Results： The ovulation rate was 61.7% （37/60） and cumulative pregnancy rate was 53.3% （32/60） with 6 months after treatment. The cases with primary infertility and/or amenorrhoea had low ovulation rate, but once ovulation was estab- lished, there was no impact on pregnancy rate; the cases with BMI 〉25kg/m2 and/or LH≤10U/L had low pregnancy rate. Conclusion： Cases with secondary infertility and without amenorrhoea have better response to B ultrasound - guided transvaginal ovarian interstitial laser treatment, and those with normal BMI and serum LH 〉 10U/L have high pregnancy rate.
出处
《中国妇幼保健》
CAS
北大核心
2009年第21期2989-2992,共4页
Maternal and Child Health Care of China
基金
深圳市科技计划(编号:200703032)
