摘要
目的：研究腺花香茶菜根的主要化学成分。方法：采用硅胶柱层析分离纯化化合物,依据理化性质和现代波谱技术进行结构鉴定。结果：从腺花香茶菜根70%丙酮提取物中分离得到6个单体化合物,分别鉴定为8（17）,13-ent-labdadien-15→16-lactone-19-oic acid（1）、腺花素（2）、乌索酸（3）、β-谷甾醇（4）、7α-羟基豆甾醇（5）、3β-羟基-5α,8α-桥二氧麦角甾-6,22-二烯（6）。结论：化合物1~6均为首次从该植物的根中获得,化合物5、6为首次从该植物中分离得到。
Objective： To explore the chemical constituents of root of Isodon adenantha.Methods： Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral analysis and chemical evidences.Results： Six compounds were obtained from ethyl acetate fraction of the extract of root of I.adenantha and were identified as 8（17）,13-ent-labda-dien-15→16-lactone-19-oic acid（1）,adenanthin（2）,ursolic acid（3）,β-sitosterol（4）,stigmast-5,22-dien-3β,7α-diol（5）,and 5,8-Epidioxy-5α,8α-ergosta-6,22E-dien-3β-ol（6）.Conclusion： Compounds 1~6 were isolated from the root of I.adenantha for the first time.while the compounds 5 and 6 were firstly obtained from this plant.
基金
国家自然科学基金资助项目(81060259)
中国热带农业科学院热带生物技术研究所中央级公益性科研院所基本科研业务费专项基金资助项目(ITBBKF1006)
云南省中青年学术技术带头人后备人才基金资助项目(2008PY005)
