摘要
以氢化诺卜醇、氯化苄和氢氧化钠水溶液为原料,苯为溶剂,在四丁基溴化铵的催化下合成了新化合物氢化诺卜醇苄基醚。通过单因素实验优化,得到氢化诺卜醇苄基醚的最佳反应条件为:n(氢化诺卜醇)∶n(氯化苄)∶n(氢氧化钠)=1∶2∶4,氢氧化钠的浓度为50%(质量分数),反应时间为7 h。产物纯化后经IR、1H NMR、13C NMR进行结构表征。
Hydronopyl benzyl ether,a novel compound,was synthesized from the reaction of hydronopol and benzyl chloride in sodium hydroxide solution with the existence of tetrabutylammonium bromide（TBAB）,benzene as solvent.The reaction conditions were optimized by single factor experiment.The optimum synthetic conditions were hydronopol∶benzyl chloride∶sodium hydroxide=1∶2∶4（molar ratio）,the content of sodium hydroxide in solution 50%（mass fraction）,reaction time 7 h.Structure of the product was identified by IR,1H NMR,13C NMR.
出处
《应用化工》
CAS
CSCD
2012年第4期578-579,583,共3页
Applied Chemical Industry
基金
国家自然科学基金项目(31060101)
江西省青年科学家(井冈之星)培养对象计划资助项目
广西林产化学与工程重点实验室开放基金资助课题(GXFC11-07)
关键词
氢化诺卜醇
苄基醚
合成
hydronopol
benzyl ether
synthesis
