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[La(C_7H_5O_2)_2(C_4H_6SO_2N)]·2H_2O的合成及体外抗肿瘤活性的初步研究

Synthesis of [La(C_7H_5O_2)_2(C_4H_6SO_2N)].2H_2O and studies on its anti-tumor Activity in vitro
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摘要 以安息香酸、诺尔卡门为配体合成了一种新的稀土配合物,用红外光谱、热重差热分析、元素分析和化学分析确定它的化学式为La(C7H5O2)(2C4H6SO2N).2H2O。体外试验表明对MCF-7的增殖有较好的抑制作用。 The complex made from reaction of lanthanum chloride heptahydrate with benzoic acid and thioproline,was characterized as [La(C7H5O2)2(C4H6SO2N)].2H2O,by IR,elemental analysis,chemical analysis and thermogravimatric analysis.The results show that the complex is effective to inhibit the proliferation of MCF-7 cell in vitro.
出处 《肿瘤药学》 CAS 2011年第6期502-504,共3页 Anti-Tumor Pharmacy
基金 湖南省教育厅资助课题(06C784) 郴州市科技局资助项目([2010]67号)
关键词 稀土配合物 抗肿瘤活性 合成 Rare earths complex Anti-tumor activity Synthesis
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