摘要
目的提高对阴茎转移性膀胱癌的认识。方法回顾性分析1例阴茎转移性膀胱鳞癌患者的临床资料,患者膀胱根治性全切术后1年,病理报告膀胱移行细胞癌3级、部分鳞化,发现阴茎根部肿块1个月。讨论其发病机制、临床诊断、治疗及预后。结果细针穿刺见到散在变性癌细胞,行根治性阴茎全切术,术后病理报告阴茎低-中分化鳞状细胞癌,结合病史,符合膀胱癌转移,海绵体及尿道均未见肿瘤浸润。术后3周行耻骨上区和双侧腹股沟区放疗1次,因出现顽固性头晕而终止。现随访17个月未发现复发和转移。结论肿瘤细胞循盆腔静脉丛及淋巴途径逆流是阴茎转移性膀胱癌发生的最可能机制;细针穿刺病理活检是安全、有效的诊断方法;治疗以根治性手术为主,辅以放、化疗等综合治疗。
Objective To improve the understanding of penis metastatic squamous carcinoma of bladder. Methods A case of penis metastatic squamous carcinoma of bladder was reported. One year after the total removal of bladder, pathology report showed level 3 transitional cell carcinoma that was partly squamous, and a lump was found at the root of the penis. The pathogenic mechanism, clinical diagnosis, treatment and prognosis were analyzed. Results Scattered degenerative carcinoma cells were found after fine - needle aspiration, and total penectomy was performed. Postoperative pathology showed differentiated squamous carcinoma of penis, which met the diagnosis criteria of bladder squamous carcinoma metastasis. There were no carcinoma cells in cavernous body of the penis and urethra. Radiotherapy was given to upper pubis and inguinal areas three weeks after operation, but was terminated due to refractory dizziness. 17 months following up showed no relapse and metastasis. Conclusion Retrograde venous and lymphatic flow in the pelvic cavity may be the mechanism for penis metastatic squamous carcinoma of bladder. Fine - needle aspiration is a safe and effective method for diagnosis, and total penectomy is the main treatment, combined with radio- therapy and chemotherapy.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第9期1032-1033,共2页
Chinese General Practice
关键词
阴茎肿瘤
膀胱肿瘤
肿瘤转移
Penile neoplasms
Urinary bladder neoplasms
Neoplasm metastasis
