期刊文献+

银屑病患者血清中sICAM-1检测的临床意义及其对病期的观察价值 被引量:4

Detecting sICAM-1 in Serum of Patient with Psoriasis and Its Observative Value of the Stage of the Disease
暂未订购
导出
摘要 目的 探讨血清中可溶性细胞粘附分子 1(sICAM 1)与银屑病 /病期的关系。方法 用ELISA法对 87例银屑病患者与 30例健康人进行血清中sICAM 1浓度的检测。结果 银屑病患者sICAM 1浓度明显增高 ,与对照组比较有显著差异 (P <0 .0 1) ,其病程、病期与浓度呈正相关。结论 sICAM 1与银屑病病期有关 。 Objective To investigate the relationship between sICAM1 and disease stage of psoriasis,Method The levels of sICAM1 in 87 patients with psoriasis and 30 normal samples were determined using ELZSA method.Results The level of sICAM1 in patients with psoriasis was significantly higher than that in controls(P<0.01) and the changes of the level were appeared positive correlation with the duration, stage of the disease.Conclusion sICAM1 may be related to the stage of psoriasis and can be the objective index of the stage of the disease.
出处 《中国皮肤性病学杂志》 北大核心 2000年第3期155-156,共2页 The Chinese Journal of Dermatovenereology
关键词 银屑病 细胞间粘附分子-1 病期观察 Psoriasis sICAM-1
  • 相关文献

参考文献5

二级参考文献8

  • 1陈峻,中国免疫学杂志,1994年,10期,224页
  • 2杨贵贞,免疫生物工程纲要与技术,1991年,201页
  • 3R. C. Beljaards,P. Van Beek,C. Nieboer,T. J. Stoof,D. M. Boorsma. The expression of interleukin-8 receptor in untreated and treated psoriasis[J] 1997,Archives of Dermatological Research(8):440~443
  • 4F. Ameglio,C. Bonifati,M. Fazio,A. Mussi,E. Trento,P. Cordiali Fei,P. Donati,F. Pimpinelli,L. D’Auria,M. Carducci. Interleukin-11 production is increased in organ cultures of lesional skin of patients with active plaque-type psoriasis as compared with nonlesional and normal skin. Similarity to interleukin-1β, interleukin-6 and interleukin-8[J] 1997,Archives of Dermatological Research(7):399~403
  • 5A. Kawada,Kenji Hara,Eiki Kominami,Masataro Hiruma,Hiromitsu Noguchi,Akira Ishibashi. Processing of cathepsins L, B and D in psoriatic epidermis[J] 1997,Archives of Dermatological Research(2):87~93
  • 6O. Wiedow,F. Wiese,E. Christophers. Lesional elastase activity in psoriasis[J] 1995,Archives of Dermatological Research(7):632~635
  • 7M. Carducci,A. Mussi,C. Bonifati,M. Fazio,F. Ameglio,L. Kowalzick,M. Weichenthal. sICAM-1, sIL-2R and beta2-microglobulin serum levels in patients affected with psoriasis: relationship with disease severity[J] 1994,Archives of Dermatological Research(7):420~422
  • 8M. A. Rie,F. Hamerlinck,R. Q. Hintzen,J. D. Bos,R. A. W. Lier. Quantitation of soluble CD27, a T-cell activation antigen, and soluble interleukin-2 receptor in serum from patients with psoriasis[J] 1991,Archives of Dermatological Research(8):533~534

共引文献35

同被引文献49

引证文献4

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部