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银屑病患者血浆中可溶性血管细胞黏附分子-1的表达研究

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摘要 目的探讨银屑病患者血浆中可溶性血管细胞黏附分子-1(sVCAM-1)的表达与银屑病疾病活动性之间的相关性。方法采用ELISA法测定40例寻常型银屑病患者治疗前后和40例健康人的血浆中sVCAM-1的水平。结果治疗前银屑病患者血浆中sVCAM-1水平高于正常人(P〈0.01),与PASI评分呈正相关(r=0.77,P〈0.01)。治疗后随病情好转,sVCAM-1水平下降(P〈0.01)。结论sVCAM-1可能参与银屑病的发病机制,其血浆水平与患者病情相关,可作为判定银屑病活动性的-个有用指标。
出处 《中国医师杂志》 CAS 2008年第5期680-681,共2页 Journal of Chinese Physician
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