摘要
目的 :分析 1976年 5月~ 1999年 10月 36例多发性骨髓瘤 ( MM)患者可能影响生存的因素。方法 :根据入院时的临床和实验室记录 ,应用 L ogrank和 COX回归分析对有关因素作单因素和多因素分析 ,并绘制Kaplan- Meier生存曲线。结果 :单因素分析发现 MM患者的生存与年龄、临床分期、骨髓浆细胞百分数 ( BMPC)、血红蛋白 ( Hb)、血清白蛋白 ( Alb)及化疗结果之间有显著相关性 ( P <0 .0 5或 <0 .0 0 1) ,多因素分析显示各因素无统计学意义。结论 :年龄、临床分期、BMPC、Hb、Alb和化疗结果与
Objective:The possible factors in influencing survival were analysed in 36 patients of multiple myeloma (MM) form 1976.5~1999.10.Methods:Kaplan Meier method was used for making the survival curve.Logrank and Cox regression model were used for univarate and multiple variate with clinical and laboratory data obtained at admission.Results:The statistical significance was obtained in univariate analysis between survival time of MM and the following univariates;age,clinical stage,bone marrow plasma cells (BMPC),hemoglobin (Hb),Alb and chemotherapeutic result (P< 0.05 or P< 0.001 ).There are no statistical significance in Cox regression Model analysis.Conclusion:Age,clinical stage,BMPC,Hgb,Alb,and chemoterapeutic result were related to survival time of MM.
出处
《临床血液学杂志》
2000年第3期114-115,共2页
Journal of Clinical Hematology
关键词
多发性骨髓瘤
随访研究
生存期
Multiple myeloma Follow-up studies Survival time