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血清皮质醇变化对慢性阻塞性肺疾病患者治疗及生活质量的影响

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摘要 目的探讨血清皮质醇水平的变化对慢性阻塞性肺疾病患者治疗及生活质量的影响。方法选择慢性阻塞性肺疾病急性加重期患者68例,入院时进行血清皮质醇测定,低于正常值低限者为观察组(27例),正常值范围者为对照组(41例),随访时间1年。分别对两组急性发作入院次数、住院时间、病死率、呼吸困难评级及生活质量评分进行观察、分析。结果观察组患者住院时间、急性发作人院次数、病死率明显大于对照组[(18.3±4.6)d比(13.0±6.0)d、(5.4±2.0)次比(2.3±1.2)次、25.9%(7/27)比19.5%(8/41)],差异有统计学意义(P〈0.05或〈0.01)。随访结束时,观察组患者呼吸困难评级、生活质量评分高于对照组[(3.82±0.70)级比(2.79±0.63)级、(56.80±5.80)分比(35.90±6.01)分],差异有统计学意义(P〈0.05或〈0.01)。结论血清皮质醇检测应为慢性阻塞性肺疾病稳定期患者选择应用糖皮质激素治疗方式的依据之一。
作者 乔华 王漫丽
出处 《中国医师进修杂志》 2012年第10期43-44,共2页 Chinese Journal of Postgraduates of Medicine
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