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来曲唑治疗全部胚胎冷冻的OHSS患者的前瞻性初步观察 被引量：1

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摘要 目的:了解来曲唑用于治疗促排卵治疗后的卵巢过度刺激综合征(OHSS)的可行性。方法:选择体外受精(IVF)周期中获卵≥30个而全部胚胎冷冻取消新鲜胚胎移植(ET)患者43例,随机分为治疗组18例,均于取卵日起口服来曲唑2.5 mg,2次/天,共5天;对照组25例予取卵后给予白蛋白、阿斯匹林等常规处理。观察两组患者轻中重度OHSS发生比率及OHSS临床自觉症状程度的差别。结果:治疗组出现中重度OHSS症状5例,明显低于对照组14例,差异有统计学意义(P<0.05);治疗组无明显OHSS症状7例,明显多于对照组2例,差异有统计学意义(P<0.05)。结论:来曲唑可以降低OHSS的发生比率和减轻其临床症状,在全部胚胎冷冻的试管婴儿患者的OHSS治疗上有一定临床运用价值。
作者 张昀 王琼 徐洪燕
机构地区 南京医科大学附属无锡市妇幼保健院 中山大学第一附属医院
出处 《中国妇幼保健》 CAS 北大核心 2012年第11期1676-1678,共3页 Maternal and Child Health Care of China
关键词 来曲唑 卵巢过度刺激综合征 体外受精-胚胎移植
分类号 R321.2 [医药卫生—人体解剖和组织胚胎学]
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参考文献17

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二级参考文献25

共引文献34

同被引文献18

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中国妇幼保健
2012年 第11期

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