摘要
目的探讨高频电刀(LEEP)在宫颈上皮内瘤变(CIN)诊治中的价值。方法回顾性分析2007年6月-2010年12月在皖北煤电集团总医院门诊就诊的宫颈上皮内病变患者78例,上述患者术前均按照宫颈病变诊疗三阶梯法,先行细胞学检查,有异常者行阴道镜检查或HPV检查,不满意者或HPV阳性者行阴道镜下多点活检确诊为CIN后,自愿接受LEEP治疗,术后均行病理诊断。结果 LEEP术后病理结果与阴道镜下多点活检病理符合率为79.2%,前者较后者病理结果有轻有重,6例CIN患者LEEP术后病理结果轻于阴道镜下活检病理结果,11例重于阴道镜下活检病理结果,其中2例CINⅢ诊断为宫颈早期浸润癌,3例CINⅡ诊断为CINⅢ。结论 LEEP可诊断和治疗CIN及宫颈原位癌,即可起到阻止浸润癌的发生,又增加了对已患浸润癌的发现率,且安全、有效、并发症少,能保留患者的生育能力,具有很好的诊断和治疗价值。
Objective This study was carried out to evaluate the effectiveness and merits of loop electrosurgical excision pro cedure（LEEP） for the treatment of cervical intraepithelial neoplasia （CIN）. Methods Retrospective analysis was performed in 78 CIN patients from June 2007 to December 2010, who were distinguished by clinic threestep diagnosis. Those women willing undertook LEEP treatment with ectocervical and endocervical excision, after resection all tissues were detected by histopathologi cal analysis. Results The pathological results in LEEP tissues were largely consistent with the result of multiple biopsies under colposcope at rate of 79.2%. By compared, some pathological changes were more severe than that in biopsies, but some others not. Six CIN eases were more lighter than that in biopsies and 11 cases were severe than that in biopsies, Meanwhile, two CIN ca ses were diagnosed as invasive cancer and three CIN 11 cases was determined as CIN 11I, using LEEP pathological analysis. Con clusion LEEP conization could be well developed in diagnosis of CIN and carcinoma in situ. In addition, it was helpful to pre vent the development of infiltrating carcinoma and promote the diagnosis ability. LEEP conization was a safe and cost effective procedure with a lower complication rate, as well as capable of maintain the eugenesis of CIN women and played a very important role in diagnosis and treatment of CIN.
出处
《中华全科医学》
2012年第4期547-547,557,共2页
Chinese Journal of General Practice
关键词
宫颈上皮内瘤变
高频电波刀环形切除术
阴道镜
Cervical intraepithelial neoplasia
Loop electrosurgical excision procedure（LEEP）
Colposcopy
