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运动、阿尔茨海默病与突触可塑性 被引量：11

Exercise,Alzheimer's Disease and Synaptic Plasticity(review)
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摘要 运动能够减缓阿尔茨海默病(AD)的发病和进展,突触可塑性可能是AD学习和记忆功能障碍的神经生物学基础,也是运动防治AD的细胞机制。本文就运动对AD的防治作用、AD突触可塑性的改变及运动对突触可塑性的影响进行综述。 Exercise can improve cognitive performance in Alzheimer＇s disease（AD）,which may involve in synaptic plasticity.This paper reviewed the benefit of exercise on AD,the synaptic plasticity in AD,and the effects of exercise on synaptic plasticity.
作者 刘慧莉 赵刚
机构地区 中国医科大学运动医学系
出处 《中国康复理论与实践》 CSCD 北大核心 2012年第3期244-246,共3页 Chinese Journal of Rehabilitation Theory and Practice
基金 国家自然科学基金(31100857)
关键词 阿尔茨海默病 运动 突触可塑性 综述 Alzheimer＇s disease exercise synaptic plasticity review
分类号 R742 [医药卫生—神经病学与精神病学]
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参考文献39

  • 1Ferri CP,Prince M,Brayne C,et al.Global prevalence of de-mentia:a Delphi consensus study[J].Lancet,2005,366(9503):2112-2117.
  • 2Um HS,Kang EB,Leem YH,et al.Exercise training acts as a therapeutic strategy for reduction of the pathogenic phenotypes for Alzheimer's disease in an NSE/APPsw-transgenic mod-el[J].Int J Mol Med,2008,22(4):529-539.
  • 3Wilson RS,Mendes De Leon CF,Barnes LL,et al.Participa-tion in cognitively stimulating activities and risk of incident Al-zheimer disease[J].JAMA,2002,287(6):742-748.
  • 4Teri L,McCurry SM,Buchner DM,et al.Exercise and activity level in Alzheimer's disease:a potential treatment focus[J].J Rehabil Res Dev,1998,35(4):411-419.
  • 5Friedland RP,Fritsch T,Smyth KA,et al.Patients with Al-zheimer's disease have reduced activities in midlife compared with healthy control-group members[J].Proc Natl Acad Sci USA,2001,98:3440-3445.
  • 6Laurin D,Verreault R,Lindsay J,et al.Physical activity and risk of cognitive impairment and dementia in elderly per-sons[J].Arch Neurol,2001,58:498-504.
  • 7Yuede CM,Zimmerman SD,Dong H,et al.Effects of volun-tary and forced exercise on plaque deposition,hippocampal volume,and behavior in the Tg2576mouse model of Alzheim-er's disease[J].Neurobiol Dis,2009,35(3):426-432.
  • 8Adlard PA,Perreau VM,Pop V,et al.Voluntary exercise de-creases amyloid load in a transgenic mouse model of Alzheim-er's disease[J].J Neurosci,2005,25(17):4217-4221.
  • 9Wolf SA,Kronenberg G,Lehmann K,et al.Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein(APP)-23model of Alzheimer's Disease[J].Biol Psychiatry,2006,60(12):1314-1323.
  • 10Richter H,Ambrée O,Lewejohann L,et al.Wheel-running in a transgenic mouse model of Alzheimer's disease:protection or symptom?[J].Behav Brain Res,2008,190(1):74-84.

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共引文献79

同被引文献154

引证文献11

二级引证文献75

中国康复理论与实践
2012年 第3期

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