期刊文献+

Lp(a)、hs-CRP、Fib与冠心病的相关性研究 被引量:3

Study of the relationship between Lipoprotein(a) and high-sensitivity C-reactive protein and fibrinogen with coronary heart disease
暂未订购
导出
摘要 目的探讨脂蛋白(a)、高敏C反应蛋白、纤维蛋白原与冠心病的相关性。方法冠心病36例确诊患者,分为稳定型心绞痛组、不稳定型心绞痛组和急性心肌梗死组,所有患者均于清晨空腹抽静脉血行Lp(a)、hs-CRP、Fib检测,并以12例健康者作为对照组。结果冠心病各组Lp(a)、hs-CRP、Fib含量较正常对照组均显著升高,急性心肌梗死组、不稳定型心绞痛组,较稳定型心绞痛组各项指标含量均明显升高,差异有统计学意义。结论 Lp(a)、hs-CRP、Fib与冠心病密切相关,对观察冠心病的严重程度和演变情况具有重要的临床意义。 Objective To investigate the relationship between Lipoprotein (α) and High-sensitivity C-reactive Protein (hs- CRP) and Fibrinogen (Fib) with Coronary Heart Disease (CHD). Methods 36 cases of diagnosed CHD patients, were divided into stable angina pectoris group, unstable angina pectoris group and acute myocardial infarction group. The fasting blood of all patients were used to detect the level of Lp (α), hs-CRP, Fib. 12 healthy persons were as controls. Results Lp (a), hs- CRP, Fib level in each CHD group compared with normal control group were significantly elevated, each index in acute myocardial infarction and unstable angina group than that in stable angina group were significantly higher. Conclusion The level of Lp (α), hs-CRP and Fib has a close relationship with CHD, which has important clinical significance to observe the severity and evolution of CHD.
出处 《中国现代医生》 2012年第10期56-57,共2页 China Modern Doctor
关键词 脂蛋白(a) 高敏C反应蛋白 纤维蛋白原 冠心病 Lipoprotein (α) High-sensitivity C-reactive protein Fibrinogen Coronary heart disease
  • 相关文献

参考文献4

  • 1Yazici M, Demircan S, Duma K,et al. Lipoprotein (a) levels in patients with unstable angina and their relationship with atherothrombosis and myocardial damage[J]. Int J Clin Pract, 2005,59 (2) : 150-155.
  • 2Rridker PM ,Cushman M,Stampfer MJ,et al. Inflammation,aspirin and the tisk of cardiovascular disease in apparently healthy men[J]. New En- gl J Med, 1997,336(4) :973-979.
  • 3师军峰.血清脂蛋白(a)、B型利钠肽(BNP)水平与冠心病的类型、病变程度的临床研究[J].陕西医学杂志,2011,40(4):412-414. 被引量:11
  • 4Meade TW. Fibrinogen measurement to assess the risk of arterial throm- bosis in individual patients : yes[J]. J Thromb Haemost, 2005,3 (4) : 632- 634.

二级参考文献14

  • 1王奇志,罗明,邓兵.脂蛋白(a)对女性冠状动脉病变程度的影响[J].临床心血管病杂志,2005,21(8):455-457. 被引量:5
  • 2布庆侠,徐军.老年男性急性脑梗死患者血Lp(a)与性激素的相关性[J].实用老年医学,2007,21(2):99-100. 被引量:4
  • 3Jame A, David A, Jane. H, et al. Prognostic value of Btype natriuretic peptide in patients with acute coronary syndromes[J]. New Engl J Med,2001,345. 1014-1021.
  • 4Bihari-Varga M. L ipoprotein (a) and the risk of coronary heart disease [J ]. Eur J Ep idemiol, 1992, 8 ( Supp 11 ) :33-35.
  • 5Rath M, Niendorf A, Reblin T, et al. Detection and quantification of Lp (a) in the arterialwall of 107 coronary bypass patients[J ]. Arteriosclerosis, 1989, 9 (5) : 579-592.
  • 6Rader DJ , Brewer HB Jr. L ipop rotein ( a ) : clinical ap-p roach to a unique atherogenic lipop rotein [ J ]. JAMA,1992, 267 (8) : 1109-1112.
  • 7Danesh J , Collins R, Peto R. L ipop rotein (a) and coronary heart disease: meta-analysis of prospective studies[ J ]. Circulation, 2000, 102 (10) : 1082-1085.
  • 8Kronenberg F, Kronenberg MF, Kiechl S, et al. Role of Lp (a) and APO (a) phenotype in atherogenesis. Prospective results from the Bruneck study [J].Circulation, 1999, 100(11) : 1154-1160.
  • 9Horie H, TakahashiM, IzumiM, et al. Association of an acure reduction in Lp (a) with coronary artery restenosis after percutaneous tvansluninal coronary angiop lasly[ J ]. Circulation, 1997, 96 (1) : 166-173.
  • 10Hunt PJ, Espiner EA, Nicholls MG, et al. The role of the circulation in processing pro -brain natriuretic peptide (proBNP) to aminoterminal BNP and BNP-82 [J] . Peptides, 1997,18(10) : 1475- 1481.

共引文献10

同被引文献33

  • 1容春莉.高密度脂蛋白胆固醇和甘油三酯与心血管病剩余风险的关系[J].中国老年学杂志,2015,35(2):349-350. 被引量:10
  • 2刘泽金,张真路,曹树正,涂茹.同型半胱氨酸、高敏C反应蛋白和纤维蛋白原与冠心病的关系[J].微循环学杂志,2005,15(4):123-124. 被引量:2
  • 3黄玮,陈庆伟,雷寒,邓玮,柯大智.纤维蛋白原与高敏C反应蛋白对稳定性冠心病患者心血管事件的预测价值[J].中华心血管病杂志,2006,34(8):718-721. 被引量:34
  • 4中华医学会心血管病学分会 中华心血管病杂志编辑委员会.急性sT段抬高型心肌梗死诊断和治疗指南.中华心血管病杂志,2010,:675-675.
  • 5吕杰,周道芹.纤维蛋白原联合高敏C反应蛋白对不稳定性心绞痛患者心脏意外事件的影响[J].中同误诊学杂志,2007,7(7):1517-1518.
  • 6Siegel D, Devaraj S,Mitra A,et al. Inflammation,atherosclerosis,and psoriasis. Clin Rev Allergy Immunol,2013 ,44(2) : 194-204.
  • 7Hofman A, Steyerberg EW, van der Lugt A, et al. Evaluation ofnewer risk markers for coronary heart disease risk classification : acohort study. Ann Intern Med,2012,156(6) :438-444.
  • 8Iqbal T,Raza N,Marwat ZI,et al. Inflammatory markers and lipidprofile in patients of coronary artery disease. J Ayub Med Coll Ab-bottabad,2011,23(3) :123-126.
  • 9吴兆苏,姚崇华,赵冬,等.11 省市队列人群心血管病发病前瞻性研究Ⅱ.个体危险因素聚集与心血管病发病的关系[J].中华心血管病杂志,2001,29(4):246-250.
  • 10Wang J, Liu ZQ, He PY,et al, Analysis of the risk factors and- characteristics of coronary artery disease of Han, Uygur and Kazak patients with acute myocardial infarction in Xinjiang distriet[J]. Int J Clin Exp Med,2015,8(2) :2831-2838.

引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部