2SkálováS,Podhola M,Vondrák K,et al.Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin(NPHS2)gene mutation.Acta Medica,2010,53:157-159.
3Traum AZ.Urine proteomic profiling to identify biomarkers of steroid re-sistance in pediatric nephrotic syndrome.Expert Rev Proteomics,2008,5:715-719.
4Chen P,Jiang T,Ouyang J,et al.Glucocorticoid receptor auto-upregula-tion and its relation with glucocorticoid sensitivity in idiopathic nephrotic syndrome.Int Urol Nephrol,2011,43:167-174.
5Ma Z,Gao X,Zhao W,et al.Relationship between expression of Pad1homologue and multidrug resistance of idiopathic nephrotic syndrome.Pe-diatr Int,2009,51:732-735.
6Jang HR,Jung HW,Lee YJ,et al.Combination treatment with corticoste-roid,cyclosporine A,and mycophenolate in refractory nephrotic syn-drome.Clin Nephrol,2011,75:511-517.
二级参考文献25
1Wing MR, Bourdon DM, Harden TK. PLC-epsilon:a shared effector protein in Ras-, Rho-, and Gαβγ-mediated signaling [ J]. Mol Interv, 2003, 3 (5):273-280.
2Kelley GG, Reks SE, Ondrako JM, et al. Phospholipase C (epsilon) :a novel Ras effector [J]. EMBO J, 2001, 20 (4):743- 754.
3Hinkes B, Wiggins RC, Gbadegesin R, et al. Positional cloning uncovers mutations in PLCE1 responsible for a nephritic syndrome variant that may be reversible [J]. Nat Genet, 2006,38 (12) : 1397-1405.
4Cockcroft S. The latest phospholipase C, PLCeta, is implicated in neuronal function [ J ] . Trends Biochem Sci, 2006, 31 ( 1 ) :4-7.
5Song C, Satoh T, Edamatsu H, et al. Differential roles of Ras and Rap 1 in growth factor dependent activation of phospholipase C epsilon [J]. Oncogene, 2002, 21 (53) :8105-8113.
6Kelley GG, Kaproth-Josln KA, Reks SE, et al. G protein.coupled receptor agenists activate endogenous phospholipase C epsilon and phospholipase C beta 3 in a temporally distinct manner [J]. J Biol Chem, 2006, 281 (5) :2639-2648.
7Evellin S, Nolte J, Tysack K, et al. Stimulation of phospholipase C-epsilon by the M (3) muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B [J]. J Biol Chem, 2002, 277 (19) :16805-16813.
8Ada-Nguema AS, Xentas H, Hofman JM, et al. The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLC epsilon [ J ] . J Cell Sci, 2006, 119 (Pt7) :1307-1319.
9Wang H, Oestreich EA, Maekawa N, et al. Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy [ J ]. Cite Res, 2005, 97 (12) :1305-1313.
10Quaggin SE, Kreidberg JA. Development of the renal glomerulus: good neighbors and good fences [ J ]. Development, 2008, 135 (4) :609-620.
10Kisner T, Burst V ,Teschner S,et al.Rituximab treatment for aduhs with refractory nephrotic syndrome: a single-center experience and review of the literature[J].Nephron Clin Pract, 2012,120(2) :c79-c85.