摘要
目的:优选芪葛口服液制备工艺参数。方法:采用黄芪甲苷含量为检测指标,通过正交设计及单因素试验考察,优选得到最佳制备工艺。结果:最佳工艺为加5倍量水,提取2次,每次2 h,醇沉体积分数60%,采用聚山梨醇酯-80(吐温-80)进行挥发油增溶。结论:芪葛口服液水提、精制工艺满足生产工艺要求。
Objective：To establish preparation technology of Qige oral liquid.Method：With the content of astragaloside iv as evaluatiom index,optimum preparation technology was optimized by orthogonal design test and single factor test.Result：Optimum technology was：extracted 2 times with 8 times the amount of water for 2 h each time,the concentration of ethanol precipitation was 60%,Tween-80 was used for solubilizing volatile oil.Conclusion：Water extracting technology and refining process of Qige oral liquid met production technology requirement.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第5期4-6,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家科技部973计划(2010CB735604)
关键词
芪葛口服液
黄芪甲苷
正交试验
增溶
澄清度
Qige oral liquid
astragaloside iv
orthogonal design
solubilizing
clarity
