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不同源性腐败梭菌产毒特性的试验 被引量:1

Experiment of Toxigenicity of Clostridium septium from Different source
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摘要 用自制的6种腐败梭菌培养基(Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ),对分离到的3株不同源性的腐败梭菌LF2010、LF9601、YF9801进行培养基和产毒能力的筛选试验。结果,此3株菌在Ⅱ号培养基上的产毒能力分别达到3 000,1 000和500MLD/mL,这为今后研制腐败梭菌疫苗的研制提供了一定的技术依据。 The screening experiment of culture - medium and toxigenicity of three strains of Closseptium (LF20101 ,LF9601 ,YF9801 ) which were from different source was conducted by six kinds of culture -medium which made by oneself( Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ ). The results showed that the toxigenicity of three strains of C. sepaum in the II culture-medium was 3000 MLD/mL,1000 MLD/mL and 500 MLD/mL)respectively,which provided the technological basis for developing the vaccine of C. septium.
出处 《青海畜牧兽医杂志》 2012年第1期16-17,共2页 Chinese Qinghai Journal of Animal and Veterinary Sciences
关键词 腐败梭菌 培养基 产毒特性 C. septiam Culture - medium Toxigenicity
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  • 1卢中华,王自振,崔保安,王亚宾,张红英,侯安祖,魏永顺,刘香仁,赵东,钱发举,董吉吉.绵羊产气荚膜杆菌与腐败梭菌混合感染[J].中国畜禽传染病,1997(4):41-43. 被引量:6
  • 2黄炯,张读朴,徐亚萍,乌斯满江,朱刚,符子华,王延,薛英.产气荚膜梭菌和腐败梭菌在厌氧菌基础培养基中的生长特性[J].动物医学进展,2005,26(4):94-98. 被引量:5
  • 3Peter JR , Pelletier MD , Plumbley MD , et al. The role ofClostridium septicum in Paraneoplastic sepsis . Archives of Pathologyand l.aboratory Medicine , 2004 , 124 (3) : 353-356.
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  • 5Jiang YW, Wang TJ , et al . The identification and structure of the membrane-spanning domain of the Clestridium septieum alpha toxin. J Bid Chem , 2004 , 279 (14) : 14315-14322.

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