摘要
从吉林栽培的伊贝母(Fritillaria pallidiflora Schrenk)鳞茎中分得6种甾体生物碱,根据其理化性质、波谱分析及化学方法鉴定为:西贝素(imperialine,Ⅰ)、西贝素甙(imperia-line-3β-D-glucoside Ⅱ)、贝母辛(peimissine,Ⅲ)、西贝素氮氧化物(imperialine N-oxide,Ⅳ)。cyclopamiae(Ⅴ)和 cycloposine(Ⅵ)。西贝素氮氧化物为自然界中首次分得的新化合物。
Six steroid alkaloids,imperialine (Ⅰ),imperialine-3β-D-glucoside (Ⅱ),peimissine (Ⅲ), imperialine N-oxide (Ⅳ),cyclopamine (Ⅴ),and cycloposine (Ⅵ) were isolated from the bulbs of Fritillaria pallidiflora Schrenk.Their structures were determined from spectral data and chemical evidences.Imperialine N-oxide was first obtained from nature.
关键词
伊贝母
生物碱
Fritillaria paliidiflora
imperialine
imperiaiine-3β-D-glucoside
peimissine
imperialine N-oxide
